INGREDIENT GUIDE
Berberine.
Read the evidence.
Know your formula.
A practical guide to research, safety, supplement labels, and the five botanicals in CoreVital Burn.
We sell Burn. This guide explains its composition and the limits of ingredient research so you can make a more informed choice. It is general education, not personal medical advice.
WHAT HAS BEEN STUDIED?
Ingredient research.
Product context.
Berberine is a plant-derived alkaloid. Researchers have studied it for metabolic outcomes, including glucose, blood lipids, and body weight. NCCIH describes the weight-loss evidence as inconclusive because study quality, formulations, and participants vary. [1]
A 2026 randomized trial enrolled 337 adults with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), without diabetes. After six months, 1 gram of berberine daily did not significantly reduce visceral fat or liver fat versus placebo. Some blood markers improved. Those findings do not establish a weight-loss benefit for Burn or predict an individual's response. [2]
Burn provides 500 mg berberine HCl per daily serving alongside four other botanicals. The trial above did not test Burn. Different amounts, preparations, and combinations cannot be treated as interchangeable. Do not increase your serving to match a research study.
BEFORE YOU START
Check fit with
your clinician.
Berberine can cause nausea, abdominal discomfort, bloating, constipation, or diarrhea. It can interact with medicines, including cyclosporine. NCCIH identifies risks for infants and advises that berberine may be unsafe during pregnancy or breastfeeding. Avoid self-starting it in these situations. [1]
Bring your full medicine and supplement list to your clinician or pharmacist before using Burn, especially if you have a medical condition or an upcoming procedure. Do not replace prescribed treatment with a supplement. Follow the marketed label, keep the bottle away from children, and do not use it if the safety seal is broken. [3]
COMPARE THE SAME THING
Forms, capsules,
and serving sizes.
Burn lists berberine HCl, a salt form of berberine. A plant extract's total weight is not necessarily its berberine content. When comparing a different form or an absorption claim, look for human research on that exact preparation and the outcome you care about; an absorption measurement alone does not establish a better health outcome. [4]
Start with the Supplement Facts serving size, then read the amount per serving and suggested use. A large number on the front of a bottle may describe multiple capsules or an entire blend. [3]
| Label detail | What it means |
|---|---|
| 2 capsules per serving | The labeled daily serving is two capsules with food. |
| 500 mg berberine HCl per serving | That is 500 mg across two capsules, equivalent to 250 mg per capsule. |
| 1,150 mg total botanicals | This includes all five botanicals. It is not 1,150 mg of berberine. |
| 60 capsules per bottle | 30 daily servings at the labeled use. |
WHAT IS IN THE BLEND?
Berberine with milk thistle
and Ceylon cinnamon.
Burn combines berberine HCl with milk thistle, Ceylon cinnamon, black cumin seed, and ginger. A standalone berberine supplement centers on berberine without this same five-botanical composition. Compare actual labels: neither a longer ingredient list nor a larger milligram number establishes that one product works better.
| Ingredient | Amount |
|---|---|
| Berberine HCl | 500 mg |
| Milk Thistle Extract | 200 mg |
| Ceylon Cinnamon Bark Extract | 200 mg |
| Black Cumin Seed Extract | 150 mg |
| Ginger Extract | 100 mg |
Other ingredients: hypromellose (capsule) and microcrystalline cellulose. These disclosed amounts describe the formula; they do not prove that the ingredients act synergistically or that the finished blend outperforms standalone berberine.
Burn is $39.95 once for one 30-day bottle, with 30 days of Wellness Circle guidance and free standard U.S. shipping. That is about $1.33 per day before applicable tax. There is no subscription. The included guidance is education, not medical treatment.
A USEFUL BUYER CHECKLIST
Read beyond
the front label.
- Identify the product. Check the brand, exact formula, capsule count, lot information, and intact seal.
- Read the complete label. Include serving size, every ingredient, directions, and warnings.
- Check the evidence behind testing claims. If a seller provides a certificate of analysis, compare the product and lot, laboratory, date, methods, and reported results. A quality seal does not establish safety or effectiveness. [3]
- Compare the complete offer. Consider cost per labeled daily serving, shipping, recurring charges, and the actual refund terms.
Burn's 45-day first-bottle satisfaction guarantee applies to one eligible first bottle per customer and household after confirmed delivery, with no bottle return required. Other eligible unopened bottles follow the separate 30-day standard return policy.
COMMON QUESTIONS
Clear answers
before checkout.
Is Burn a standalone berberine supplement?
No. Burn has 500 mg berberine HCl plus four botanicals in each two-capsule serving. It also includes 30 days of Wellness Circle guidance. Compare the full ingredient list when deciding whether a blend fits your needs.
Does each capsule contain 500 mg of berberine?
No. The 500 mg amount is per two-capsule serving. One bottle has 60 capsules, or 30 servings. Follow the labeled directions of two capsules daily with food.
Is a berberine blend proven better for weight loss?
The ingredients and their amounts alone cannot establish that. Evidence for a particular ingredient or another blend does not prove Burn's finished formula produces the same result. No specific weight-loss result is promised.
Where can I ask about the label or my order?
Contact CoreVital support for product and order questions. For medication interactions or whether a supplement is appropriate for you, speak with your clinician or pharmacist. You can also learn about Samir Bute, MD, the physician behind Burn.
READ THE ORIGINAL SOURCES
Evidence you
can inspect.
- NCCIH: Berberine and Weight Loss—What You Need To Know. Updated November 2023. Research limitations and safety.
- Berberine and Adiposity in Diabetes-Free Individuals With Obesity and MASLD: A Randomized Clinical Trial. 2026. PMID 41543854.
- NIH Office of Dietary Supplements: Dietary Supplements—What You Need to Know. Updated January 2023. Labels, safety, and quality testing.
- Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery. 2010. Laboratory formulation research, not evidence of Burn's clinical effects.
Sources accessed September 19, 2026. Product amounts and offer details reflect the CoreVital Burn product listing. References do not imply that NIH or the study authors endorse Burn.